Publications & Results

Scientific publications

Uncovering combination therapies for immune-mediated inflammation diseases through systems biology analysis on longitudinal patient data

Author: Sergio H. Martínez-Mateu, Yolanda Guillén, Edgar Angelats, María A. López-Lasanta, Stefania Madonna, Laura Jiménez-Gracia, Ivan Rodriguez-Nunez, Damiana Álvarez-Errico, Adrià Aterido, Raül Tortosa, Max Ruiz, Pau Serra, Juan D. Cañete, Jose M. Carrascosa, Eugeni Domènech, Javier P. Gisbert, Jesús Tornero, IMID-Consortium, Britta Siegmund, Giampiero Girolomoni, Ernest H.S. Choy, Richard M. Myers, Holger Heyn, Pere Santamaria, Sara Marsal, Antonio Julià

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Press Releases

DocTIS unveils major scientific outcomes for immune-mediated inflammatory diseases

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Datasets

DocTIS Research Data and Code Repositories

Author: DocTIS consortium

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Public deliverables

Deliverable 8.4 – Midterm recruitment report UPDATE

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Scientific publications

Biosimilars for chronic plaque psoriasis: a 2026 update

Author: Martina Maurelli, Andrea Danese, Paolo Gisondi & Giampiero Girolomoni

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Scientific publications

Decision on optimal combinatorial therapies in immune-mediated inflammatory diseases using systems approaches (DocTIS): protocol for a single-arm, adaptive basket trial in rheumatoid and psoriatic arthritis

Author: Rory Sheppard, Myrsini Gianatsi, Ian Thomas, Sophie King, David Gillespie, Philip Pallmann, Sara Marsal Barril, Ernest Choy

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Scientific publications

Integrative CSF profiling identifies disease-specific immune responses in leptomeningeal disease

Author: Paula Nieto, Svenja Klinsing, Ginevra Caratù, Mareike Dettki, Domenica Marchese, Katharina J. Weber, Samuel Morabito, Patricia Lorden, Irene Ruano, Katharina Imkeller, M. Angels Velasco, Silvia Vidal, Juan L. Melero, Philipp Euskirchen, Marcus Czabanka, Karl H. Plate, Patrick N. Harter, Anna Pascual-Reguant, Joachim P. Steinbach, Holger Heyn, Pia S. Zeiner, Juan C. Nieto

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Scientific publications

Interpretable inflammation landscape of circulating immune cells

Author: Laura Jiménez-Gracia, Davide Maspero, Sergio Aguilar-Fernández, Francesco Craighero, Maria Boulougouri, Max Ruiz, Domenica Marchese, Ginevra Caratù, Jose Liñares-Blanco, Miren Berasategi, Ricardo O. Ramirez Flores, Angela Sanzo-Machuca, Ana M. Corraliza, Hoang A. Tran, Rachelly Normand, Jacquelyn Nestor, Yourae Hong, Tessa Kole, Petra van der Velde, Frederique Alleblas, Flaminia Pedretti, Adrià Aterido, Martin Banchero, German Soriano, Eva Román, Maarten van den Berge, Azucena Salas, Jose Manuel Carrascosa, Antonio Fernández Nebro, Eugeni Domènech, Juan Cañete, Jesús Tornero, Javier P. Gisbert, Ernest Choy, Giampiero Girolomoni, Britta Siegmund, Antonio Julià, Violeta Serra, Roberto Elosua, Sabine Tejpar, Silvia Vidal, Martijn C. Nawijn, Ivo Gut, Julio Saez-Rodriguez, Sara Marsal, Alexandra-Chloé Villani, Juan C. Nieto & Holger Heyn.

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Scientific publications

A transcriptional map of human tonsil architecture: beyond the sum of (single cell) parts

Author: Helena L. Crowell, Laura Llaó-Cid, Gerard Frigola, Samuel Gunz, Irene Ruano, Patricia Lorden, Max Ruiz, Marta Kulis, José Ignacio Martin-Subero, Holger Heyn, Elias Campo, Anna Pascual-Reguant.

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Abstract Publications

Uncovering combination therapies for Immune-Mediated Inflammatory Diseases through systems biology analysis on longitudinal patient data 3497

Author: Antonio Julià, Maria López Lasanta, Ernest Choy, Paloma Vela-Casasempere, Santos Castañeda, Antonio Fernandez Nebro, Jaime Calvo-Alén, Carlos Marras, Jesus Tornero, Juan D. Cañete, Eugeni Domènech, Javier Gisbert, José Manuel Carrascosa, Eduardo Fonseca, Luis Bujanda, Valle García, Britta Siegmund, Giampiero Girolomoni, Holger Heyn, Pere Santamaria, Richard Myers, Yolanda Guillen, Sergio H. Martínez-Mateu, Sara Marsal

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The DoCTIS project has received funding from the European Union’s H2020 research and innovation program under grant agreement 848028.