DocTIS findings to be presented at UEG Week 2025
The upcoming United European Gastroenterology Week (UEG Week), the premier annual congress in Europe focused on gastroenterology and digestive health, will feature important findings from the DocTIS project. UEG Week 2025 will take place October 4–7 in Berlin (and online), bringing together a multidisciplinary, international community of clinicians, researchers, allied health professionals, and industry partners to share cutting-edge science, clinical practice, and education.
On Monday, October 6, at 08:30 in Room A3 of Messe Berlin (Entrance: CityCube), Professor Britta Siegmund, Principal Investigator of the DocTIS project at Charité – Universitätsmedizin Berlin, and Director of the Department of Gastroenterology, Infectious Diseases and Rheumatology, will present “DocTIS: A Single-Cell RNA-seq Atlas of Drug Response to Targeted Therapies in Immune-Mediated Inflammatory Diseases” as part of the abstract session “Molecular medicine: Understanding the mechanism allows therapy”.
The study provides the first large-scale single-cell RNA sequencing (scRNA-Seq) analysis of drug responses in immune-mediated inflammatory diseases (IMIDs). The findings highlight distinct immune patterns across diseases, key differences between responders and non-responders, and offer a detailed map of immune mechanisms underlying drug efficacy, advancing prospects for more precise and effective treatments.
The research was developed by the DocTIS scientific partners — IMIDomics Inc., Charité – Universitätsmedizin Berlin, the University of Verona, the Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), the HudsonAlpha Institute for Biotechnology, the Vall d’Hebron Research Institute (VHIR), Cardiff University and the National Center for Genomic Analysis (CNAG) — in close collaboration with a large network of hospitals in Spain through the IMID Consortium, providing access to diverse patient cohorts and robust clinical data.
About UEG Week
Held annually, UEG Week is a recurring focal point in the gastroenterology calendar of Europe, attracting more than 11,500 delegates from over 115 countries in its 2024 edition and showcasing its broad global reach and appeal. The congress is organized by United European Gastroenterology (UEG), a leading non-profit representing over 50,000 digestive health professionals across Europe.
The full scientific programme is available at: https://programme.ueg.eu/2025.
